Cadillac Series 452Cs for Sale In hopes of outcompeting Packard in the big engine game, General Motors created a V16 in the 1930s that powered the Cadillac Series 452C. This big luxury car, run by the multi-cylinder engine was the peak of extravagance in 1933 America. The 452s were a little bit too much car and too much money for the average buyer and not many models were produced. This means that if you can find one today, you have a real collector’s item. FossilCars has the comprehensive list of classified to help you find a Cadillac Series 452C.